Gewicht, serumlipiden en bloedglucosespiegels kunnen toenemen tijdens de behandeling met cART. Diabetes mellitus. Because there is clear benefit to appropriate treatment, maternal ART should not be withheld due to concerns for adverse neonatal outcomes. Als onderdeel van een antivirale combinatietherapie voor de behandeling van een HIV-1-infectie, alleen indien andere antiretrovirale geneesmiddelen niet kunnen worden gebruikt. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Indien dit niet mogelijk is, hervatting van de behandeling met een lagere dosis overwegen onder strikte controle van symptomen van perifere neuropathie. • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Find out what health conditions may be a health risk when taken with Stavudine Oral Antiretrovirale combinatietherapie (cART) is in verband gebracht met gewichtstoename en metabole stoornissen (zoals hypercholesterolemie, hypertriglyceridemie, hyperglykemie en insulineresistentie). Klap alles dicht. 70% onveranderd; ca. The appearance of advertisement or product information in the various section in the website does not constitute an endorsement or approval by Pediatric Oncall of the quality or value of the said product or of claims made by its manufacturer. 40% van plasmaconcentratie. Note: This is not a comprehensive list of all side effects. Caution should be exercised in patients with history of liver or kidney disease, sugar, elderly, during pregnancy and breastfeeding. Stavudine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA. Older patients should be closely monitored for signs and symptoms of peripheral neuropathy. stavudine vergelijken met een ander geneesmiddel. Redistribution/accumulation of body fat including central obesity may occur. Available for Android and iOS devices. dialysepatiënten): lichaamsgewicht ≥ 60 kg: 20 mg elke 24 uur; < 60 kg: 15 mg elke 24 uur. Wees voorzichtig bij een voorgeschiedenis van perifere neuropathie. Hepatotoxicity or lactic acidosis, including fatal cases, have been reported with the use of stavudine. Zelden (0,01–0,1%): anemie. Stavudine passeert de placenta. Dose as in GFR<25 mL/min, Unknown dialysability. Nucleoside reverse transcriptaseremmer (NRTI). Aan de vergoeding van dit geneesmiddel zijn bepaalde voorwaarden verbonden, die zijn vermeld op bijlage 2 van de Regeling zorgverzekering. May be administered without regard to meals. Advies: Alleen op strikte indicatie gebruiken. HIV-1 infection, treatment: Note: Although FDA approved, stavudine is no longer recommended for use in pediatric patients due to higher rates of adverse effects than other nucleoside reverse transcriptase inhibitors (HHS [adult, pediatric] 2018). 3% met de feces. De behandelduur zo kort mogelijk houden en zo mogelijk omschakelen naar een andere behandeling. It comes as a capsule and liquid to take by mouth with or without food. perifere neuropathie, paresthesie en perifere neuritis, duizeligheid, hoofdpijn, slapeloosheid, slaperigheid, vermoeidheid, depressie, abnormale dromen en gedachten. Antiviral effect inhibited by zidovudine, doxorubicin and ribavirin. Zo nodig kan de toediening ook plaatsvinden door de capsule voorzichtig te openen en de inhoud met voedsel te mengen. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Stavudine SELECT Concise Prescribing Info Full Prescribing Info Dosage/Direction for Use Administration Contraindications Special Precautions Adverse Reactions Pregnancy Category (US FDA) Overdosage Drug Interactions Food Interaction Action Storage CIMS Class ATC Classification
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